I had a quick look, but sorry my knowledge of Payara is close to zero and I have no idea of what it’s doing. Might be best to ask the Payara developers.

From the error and the stacktrace it doesn’t seem related to our own bytecode enhancement, as it hasn’t been initialized (it’s actually failing to initialize the bytecode transformer..); it would seem like there is some issue with modular classloading or possibly a library conflict?