About xulrunner's nsISelection:
anchor
The anchor of a selection is the beginning point of the selection. When making a selection with a mouse, the anchor is where in the document the mouse button is initially pressed. As the user changes the selection using the mouse or the keyboard, the anchor does not move.
focus
The focus of a selection is the end point of the selection. When making a selection with a mouse, the focus is where in the document the mouse button is released. As the user changes the selection using the mouse or the keyboard, the focus is the end of the selection that moves.

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